HOPO(2-Pyridinol-1-oxide) can be used as an additive during peptide synthesis to reduce racemization and thereby increase chiral purity of the final product. Its solubility in water makes it especially useful during solution-phase peptide synthesis. HOPO has also shown to be useful in other applications, including the functionalization of self-assembled monolayers.

CAS: 13161-30-3

Synonym: 2-Hydroxypyridine-N-oxide